Antibodies are molecules of glycoprotein nature that have ability to bind antigens either soluble or bound in membranes of cells in a specific way. They are present in plasma and in tissue fluids (lymph, saliva, tears etc.). As most of antibodies belong to the gamma globulins of plasma proteins, they were previously known under the term gammaglobulins; their contemporary nomenclature is immunoglobulins (Ig). There are five classes of immunoglobulins: IgG, IgM, IgA, IgE, and IgE, respectively. They have specific biochemical structure and function. The principal biological role is to bind antigens; except it, they can activate the complement, opsonise bacteria, bind to receptors of various cell of the immune system etc.
Serological methods II
.. are basic diagnostic methods used to identify antibodies and antigens in patient sample. Up-to-date.. ..keywords: methods, antigen, antibodies, ELISA, RIA,.. ..keywords: methods, antigen, antibodies, ELISA, RIA,..
Serological methods I
.. are basic diagnostic methods used to identify antibodies and antigens in patient sample (serum, plasma)...
Type I hypersensitivity (Allergy)
..Antibodies belonging to IgE class mediate this type of.. ..keywords: anaphylaxis, atopy, IgE antibodies,..
The complent system and its biological significance
..Antibodies manage to protect us against germs principally.. ..keywords: Antibodies, complement, lysis of target cells, imune..
B lymphocytes and plasma cells
.. interaction with foreign antigens. Production of antibodies is initiated by the interaction of antigens with.. .. interaction with foreign antigens. Production of antibodies is initiated by the interaction of antigens with..
Foeto-maternal relationships. The immune system of newborns
.. the child´s life, it is protected by IgG antibodies that crossed the placenta. They protect the..
Milestones of Immunology, Immune system - an overview, Antigen
.. also billions of molecules, approximately 1020 (antibodies, cytokines, regulatory, anti-microbial,..
Hypersensitivity reactions, types II till V
.. induce different immune effector molecules. IgE antibodies, for example, induce mast cell degranulation.. .. by blood-transfusion reactions, in which host antibodies react with foreign antigens on the incompatible..
Autoimmunity and autoimmune disease
.. in healthy individuals failure to produce autoantibodies against self-protein antigens is due from lack.. ..keywords: T cells, B cells, antibodies, genes, therapy,..
Ophthalmooncology - Tumors of the Orbit
.. adverse effects, but treatment with monoclonal antibodies against a surface receptor (CD20) on the..