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Milestones of Immunology, Immune system - an overview, Antigen
Common people perceive Immunology as a scientific branch that studies defence of an organism against germs, cancer cells, toxins etc. Nowadays, Immunology is defined a scientific branch that studies immunity, its cellular and molecular processes that proceed after a foreign substance, an antigen, enters our body. There are many notable personalities who contributed to its development. Let us mention only some of them – Louis Pasteur, Ilja Mecnikov, Jean Dausset and many, many others. They contributed to the fact that Immunology belongs to those scientific disciplines that develop the most intensively in recent years.
Foeto-maternal relationships. The immune system of newborns
A success of pregnancy depends on a proper implantation and induction of immune tolerance. The immune system secures it by various mechanisms – special cells, cytokines, HLA molecules, peripheral tolerance take part in.
The immune system of the newborn has also its own specifics as it matures relatively long time till it reaches the same protective ability as characteristic for adults.
Structure of Matter From Biophysical Point of View
The lecture „Structure of Matter From Biophysical Point of View“ is aimed to give a brief introduction to some applications of physics at microscopic level in medicine. It explains the fundamental problem of science, gives an overview of important stages in structure analysis, explains different structure and forms of matter, physical interactions, general properties and characteristics of matter, Heisenberg uncertainty principle, basic properties of elementary particles, the principle and usefulness of Schrödinger equation.
Physiology of Cardiovascular system 2
ECG description, basic pathological findings, step to step description of ECG.
ENDOCRINE SYSTEM - part I
Endocryne system of the human body.
Decription of the endocrine system - part I. The lecture for the 1st year medical students - Dentistry branch (English Programme): describes the role, structures of the system. Provides also the description of the thyroid and parathyroid glands, adrenals, endocrine part of pancreas and pituitary gland.
Physiology of central nervous system 6
Physiology of speech and speech laterality.
Physiology of central nervous system 5
Physiology of memory and learning, spatial learning, general intelligence
Physiology of central nervous system 4
Physiology of emotions, emotion intelligence, anger, fear, happiness.
Physiology of central nervous system 3
Physiology of higher brain fiunctions, cortical syndromes, sleep physiology.
Physiology of central nervous system 2
Sensory hierarchy of CNS, vision, hearing, pain perception.
Physiology of central nervous system 1
Ontogenesis and development of central nervous system.
The complent system and its biological significance
Antibodies manage to protect us against germs principally by two ways: by enveloping their surfaces (opsonisation), what makes their engulfment and killing by phagocytes easier and more effective or by cell lysis. However, in this case, they need a help from the complement system.
Cardiovascular physiology - lymphatic system
Lymphatic vessels (lymphatic capillaries, collecting vessels, collecting ducts), lymph (origin, composition, formation), lymph flow (intrinsic and extrinsic mechanism), lymphatic tissues and organs (lymph nodes, mucosa associated lymphoid tissue - MALT, spleen, thymus), functions of lymphatic system.
ENDOCRINE SYSTEM - part II
Continuation of the endocrine system description.
Endocrine system - part II. The lecture for the 1st year medical students - Dentistry branch (English programme) - continuation of the part I: describes regulatory role of hypothalamus, pineal gland, thymus, gonadal glands and also chromaffine cells system.
Clinical anatomy of the cardiovascular system
Describes the clinical antomy of the structures of the cardiovascular system: heart and vessels.
Clinical anatomy of the cardiovascular system- the lecture for the 4th year medical students (General Medicine branch), compulsory optional subject Clinical anatomy - summer semester. The lecture provides the description of the cardiovascular system structures from their clinical anatomical point of view.
Clinical anatomy of the lymphatic system
Clinical anatomy of the lymphatic system.
Clinical anatomy of the lymphatic system - the lecture for the 4th year medical students (General Medicine branch), compulsory optional subject Clinical anatomy. Provides the descriptom of the lymphatic system structures from the point of view of the clinical anatomy.
Komplementový systém a jeho biologický význam
Protilátky nás pred mikroorganizmami chránia principiálne dvoma spôsobmi: obaľovaním ich povrchu (opsonizácia), čo uľahčuje ich pohltenie a usmrtenie fagocytmi, alebo ich lýzou. V tomto poslednom prípade však potrebujú pomoc zo strany komplementového systému. Tento tvorí viac ako 35 proteínov, ktoré produkuje najmä pečeň a makrofágy, čo umožňuje jeho aktiváciu kdekoľvek v organizme kde prebieha zápal. Zložky komplementu sú súčasťou proteínov plazmy a reprezentujú 10% z globulínovej frakcie.
Míľniky vývoja imunológie. Imuntný systém - prehľad. Antigén
Verejnosť vníma imunológiu ako vednú disciplínu, ktorá sa zaoberá štúdiom obranných mechanizmov proti mikroorganizmom, infekčným chorobám. Dnes však Imunológiu vnímame širšie, ako vednú disciplínu, ktorá študuje bunkové a molekulové procesy, ktoré sa odohrávajú v organizme človeka, či zvierat alebo rastlín po vniknutí akejkoľvek cudzej látky do tela. K rozvoju imunológie prispeli početné významné osobnosti, zmieňme sa len o takých velikánoch ako boli Louis Pasteur, Ilja Mečnikov, Jean Dausset a mnohí, mnohí ďalší; svedčia o tom Nobelove ceny, ktoré sa skoro každé 3 – 4 roky dostanú vedeckí pracovníci na poli imunológie. Táto skutočnosť je odrazom prudkého rozmachu tohto fascinujúceho vedného odboru a jeho veľkému významu pre biológiu a medicínu.
Antibodies. B cells
.. respectively. They have specific biochemical structure and function. The principal biological role is.. .. in a specific way. They are present in plasma and in tissue fluids (lymph, saliva, tears etc.). As.. .. They have specific biochemical structure and function. The principal biological role is to bind.. .. are molecules of glycoprotein nature that have ability to bind.. .. nature that have ability to bind antigens either soluble or bound in membranes of cells in a.. .. bind to receptors of various cell of the immune system.. .. bind to receptors of various cell of the immune system.. .. are produced by B lymphocytes and especially by plasma cells. B cells are born in.. .. occupy lymphoid follicles. They comprise 15% of all peripheral blood lymphocytes and are.. .. especially by plasma cells. B cells are born in the marrow and settle secondary lymphoid organs,.. ..of. MUDr. Milan Buc, DrSc. Attachments:..
Blood physiology
.. - composition, functions. Erythrocytes and their function, haemoglobin. Blood groups... .. on blood physiology.
Blood - composition, functions. Erythrocytes and their function, haemoglobin... .. to the lecture on blood physiology.
Blood -.. .. Platelets and haemostasis. Leukocytes and their immune unctions. Plasma - composition, function,.. ..keywords: - composition, function..
Blood Physiology (Lecture for the Dentistry Students)
.. - composition and function. Blood and homeostasis. Red blood.. .. - composition and function. Blood and homeostasis. Red blood elements,.. .. rate, haematocrit. Leukocytes - types and their immune functions. Platelets and haemostasis... .. rate, haematocrit. Leukocytes - types and their immune functions. Platelets and haemostasis... ..keywords: composition and function, haemopoiesis, blood.. ..keywords: composition and function, haemopoiesis, blood.. .. [?]
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Blood Physiology (Lecture for the Dentistry Students)
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10.3.2016
3.79 MB
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Cytokines. PAMPs and PRRs
.. peptides that induce activation, proliferation and differentiation of cells of the immune system... .. the immune system. Moreover, cytokines influence functions of cells of other tissues and organs, esp. of.. .. activation, proliferation and differentiation of cells of the immune system. Moreover, cytokines.. .. proliferation and differentiation of cells of the immune system. Moreover, cytokines influence.. .. and differentiation of cells of the immune system. Moreover, cytokines influence functions.. .. and differentiation of cells of the immune system. Moreover, cytokines influence functions of.. .. patterns (PAMPs”) was coined for them and receptors recognising them are called.. .. immunity recognises an infinite variety of antigens by millions of cell-surface receptors... .. by millions of cell-surface receptors. Instead, the innate immune system recognition of antigens is.. .. of cell-surface receptors. Instead, the innate immune system recognition of antigens is based on a.. .. receptors. Instead, the innate immune system recognition of antigens is based on a much.. ..keywords: interleukins, molecular patterns of.. .. sensitive [?]
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Cytokines. PAMPs and PRRs
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16.3.2012
11.09 MB
MEFANET.. ..of. MUDr. Milan Buc, DrSc. Attachments:..
Practicals_Blood 4
.. description of immune system, types of leukocytes, blood.. .. description of immune system, types of leukocytes, blood.. .. description of immune system, types of leukocytes, blood..
Antigen presentation; T cell mediated immunity
.. them to T cells; moreover, they activate them and polarise to a specific biological functions... .. them and polarise to a specific biological functions. Depending of antigen origin, there are two.. .. to a specific biological functions. Depending of antigen origin, there are two presentation.. .. by antigen presenting cells (APCs). Following their processing that comprises their splitting to.. .. antigens are no able to induce an immune response without being previously processed by.. .. that express αβ T cell receptors and those that express γσT cell.. .. subset mediates different biological effector functions, such as activation of macrophages, NK cells,.. .. cells are not unique population of cells. There are two basic subpopulations, those.. .. cells are not unique population of cells. There are two basic subpopulations, those that.. .. as well as APC, B cell and other cell of the immune system, is regulated by regulatory T cells.. .. well as APC, B cell and other cell of the immune system, is regulated by regulatory T cells (Tregs)... ..keywords: presenting cells, HLA molecules, T cells and their.. ..keywords: presenting cells, HLA molecules, T cells and their.. ..of. MUDr. Milan Buc, DrSc. Prílohy:
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Immunodeficiencies. AIDS
.. lecture deals with primary and secondary immunodefeciencies. It gives an.. .. divisions according to the type of the immune functions defects. Must of the lecture devotes to.. .. and their divisions according to the type of the immune functions defects. Must of the.. ..The lecture deals with primary and secondary.. .. and their divisions according to the type of the immune functions defects. Must of the lecture devotes.. .. caused by human immunodeficiency type I (HIV-1) and II (HIV-2) viruses, respectively. HIV-1 was.. .. 1983 and HIV-2 in 1986. HIV-1 is the major cause of AIDS in the world today. Worldwide, the number.. .. discovered in 1983 and HIV-2 in 1986. HIV-1 is the major cause of AIDS in the world today... .. meat.
HIV infects a variety of cells of the immune system, including CD4-expressing helper T cells,.. .. infects a variety of cells of the immune system, including CD4-expressing helper T cells,.. ..of. MUDr. Milan Buc, DrSc. Prílohy:
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Organic chemistry
.. to students basic organic compouds, their structure and properties in relation to biologically.. .. students basic organic compouds, their structure and properties in relation to biologically important.. .. from organic chemistry is designed for students of general medicine. The content of lecture.. .. is designed for students of general medicine. The content of lecture represents the introduction.. ..of. Ing. Zdeňka Ďuračková, PhD. Prílohy:
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Autoimmunity and autoimmune disease
.. potentially threatening our life, i.e. infection and malignancy. However, sometimes the immune system.. .. principal role of the immune system is to protect the organism.. ..The principal role of the immune system is to.. .. principal role of the immune system is to protect the organism from.. .. principal role of the immune system is to protect the organism from principally two.. .. property of the normal immune system, and failure of self-tolerance results in immune.. .. (MHC, i.e. the HLA complex in humans), and the function of MHC molecules is to present peptides to T.. .. called self-tolerance, is a fundamental property of the normal immune system, and failure of.. .. When specific lymphocytes encounter antigens, the lymphocytes may be activated, leading to immune.. .. the lymphocytes may be activated, leading to immune responses, or the cells may be inactivated or.. .. is a fundamental property of the normal immune system, and failure of self-tolerance results in immune.. ..keywords: T cells, B cells, antibodies, genes, therapy,.. .. citlivé [?]
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Autoimmunity and autoimmune disease
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9.4.2013
8.34 MB
MEFANET.. ..of. MUDr. Milan Buc, DrSc. Prílohy:
Príloha
.. .. citlivé [?]
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Autoimmunity and autoimmune disease
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9.4.2013
8.34 MB
MEFANET..
HLA complex and its significance in biology and medicine
.. determined proteins present in membranes of all nucleated cells. They form a unique system.. .. present in membranes of all nucleated cells. They form a unique system for which the term.. .. of all nucleated cells. They form a unique system for which the term “Major.. .. on the short arm of chromosome 6 (6p21.3) and occupies a large segment of DNA, extending about.. .. genetic region of the HLA complex is located on the short arm of.. ..The genetic region of the HLA complex is located on.. .. are involved in cooperation of cells o the immune system and are indispensable for tolerance.. .. involved in cooperation of cells o the immune system and are indispensable for tolerance induction... ..keywords: molecules, HLA system, chromosome 6, antigen presentation,.. .. citlivé [?]
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HLA complex and its significance in biology and.. ..of. MUDr. Milan Buc, DrSc. Prílohy:
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