Multimedia support in the education of clinical and health care disciplines :: Portal of Faculty of Medicine in Bratislava
Faculty of Medicine, Comenius University in Bratislava
Comenius University in Bratislava
MEFANET (MEdical FAculties Educational NETwork) Project

Microbiology 1 [023]

Sorted by: priority and last modification time
 

B lymphocytes and plasma cells

B lymphocytes and plasma cells

B lymphocytes are principal cells that mediate humoral adaptive immunity. After their maturation in the bone marrow, B cells enter peripheral lymphoid tissues, which are the sites of interaction with foreign antigens. Production of antibodies is initiated by the interaction of antigens with a small number of mature B cells specific for each antigen. An antigen binds to the membrane receptors on specific B cells and initiates a series of responses that lead to two principal changes: cell proliferation resulting in expansion of the clone, and differentiation to either plasma cells actively secreting antibodies or to memory cells.

Key words: B cells, subsets of B cells, memory B cells, plasma cells

 
author: Milan Buc | discipline: Immunology, Allergology | viewed: 6280x | published on: 6.3.2017 | last modified on: 6.3.2017