prof. MUDr. Ján Koller, koller(at)nspr.sk
Human skin seems to be simply external coverage of the human body. This statement is not completely true, as human skin, in addition to its protective function from the external environment, does have a range of other functions such as mechanical barrier, external immune barrier, participation in thermoregulation, excretion of sweat and sebum, sensory functions, and identification functions for the human being. Skin is the largest organ of the human body, as its average surface in adult persons is about 2 m2 and its total mass is about 5 kg. An extensive burn injury affecting more than 20% of the body surface area, can lead to temporary, or permanent dysfunction or failure of the skin organ which could become a life threatening situation.