EPIBULBAR LESIONS

Epibulbar lesions are formed particularly in the conjunctiva and cornea. These lesions are classified into two distinct types that include pigmented and non-pigmented epibulbar lesions. The pigmented epibulbar lesions are those lesions that have pigments while the non-pigmented lesions are those that are translucent or transparent due to the absence of the pigments.         

 

Epibulbar pigmented lesions include conjunctival epithelial melanosis, conjunctival freckle, primary acquired melanosis (PAM), conjunctival nevus, congenital ocular melanocytosis, melanoma and orbital melanoma.
Non-pigmented epibulbar lesions include papilloma epibulbar choristoma, pyogenic granuloma, conjunctival intraepithelial neoplasia (carcinoma in situ, dysplasia), conjunctival squamous cell carcinoma, conjunctival Kaposi sarcoma, conjunctival lymphoma, mucoepidermoid carcinoma, and infiltration from lid tumors.
These lesions can be benign, malignant and premalignant which have high prevalence among the Caucasian population. However, the reason of the prevalence of these lesions in a particular population is not known.
Further studies are recommended to provide an in-depth analysis of the effectiveness of different treatments that can be used for the treatment of the epibulbar and non-pigmented pigmented lesions.


In attached file we give an overview of epibulbar lesions.

 

References

  1. Al-Faky Y (2012) Epidemiology of benign eyelid lesions in patients presenting to a teaching hospital. Saudi Journal of Ophthalmology 26(2): 211–216 http://www.sciencedirect.com/science/article/pii/S1319453411000646
  2. Carol L. Shields, M., and Jerry A. Shields, MD (2004). "Tumors of the Conjunctiva and Cornea." Survey of ophthalmology 49(1): 3-24, http://www.surveyophthalmol.com/article/S0039-6257(03)00130-9/fulltext
  3. Furdova A, Pesko K, Strmen P, Kobzova M.Conjunctival nevus and melanoma.Bratisl Lek Listy. 2007;108(7):287-91 http://www.ncbi.nlm.nih.gov/pubmed/17972544
  4. Gustavo A. Novais, M., and Carol L. Karp, MD (2010). "Diagnosis and Management of Conjunctival Melanoma." Ophthalmic Pearls: Oncology: 37-38. http://www.aao.org/publications/eyenet/201007/pearls.cfm
  5. Huerva V and Ascaso F (2012). Conjunctival Intraepithelial Neoplasia – Clinical Presentation,Diagnosis and Treatment Possibilities, chapter (4), p, 80-100, http://cdn.intechopen.com/pdfs-wm/27762.pdf
  6. Kalpana Pandey, Parul Singh, ( 2011) Abhishek. Primary sebaceous gland carcinoma of the bulbar conjunctiva without involvement of eyelid: A clinical dilemma ,Oman J Ophthalmol. 2011 May-Aug; 4(2): 97–99. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160081/
  7. Kanski J and Bowling B (2011) Clinical Ophthalmology: A Systematic Approach, 7th Edition. Elsevier Health Sciences, p. 1-890. eBook ISBN :9780702045110 http://store.elsevier.com/product.jsp?locale=en_US&isbn=9780702040931
  8. Kanski J Jack, (2010). Signs in opthalomlogy causes and differntial diagnosis . Elsevier Health Sciences . 1st Edition. Chapter 3, p-82-88 , eBook ISBN :9780723436966, http://store.elsevier.com/Signs-in-Ophthalmology-Causes-and-Differential-Diagnosis/Jack-Kanski/isbn-9780723435488/
  9. Litak J, Dimitropoulos V, Dy L, Brown C, Grostern R (2012) Conjunctival Papilloma. Cutis, 2012 Jan;89(1):38-40.http://www.ncbi.nlm.nih.gov/pubmed/22439310
  10. Shields J, and Shields C (2008). Eyelid, Conjunctival, and Orbital Tumors: An Atlas and Textbook. Lippincott Williams & Wilkins. 2nd edition, part 2 Tumors of the conjunctiva , p 249-437 , ISBN-13 978-0-7817-7581-6. http://www.amazon.com/Eyelid-Conjunctival-Orbital-Tumors-Atlas/dp/0781775787

Podporené grantom KEGA 008 UK - 4/2014.

 

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